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In fibrosis development and progression, myofibroblasts play a pivotal role, producing extracellular matrix and interacting with various resident cells in the kidney. Over the past decade, the origin of myofibroblasts has been thoroughly investigated. Emerging evidence suggests that renal myofibroblasts originate S100A8/A9 appears as a Janus-faced molecule. It is a powerful apoptotic agent produced by immune cells, making it a very fascinating tool in the battle against cancer.
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Dynamics of raft molecules in the cell and artificial membranes: Approaches by pulse EPR spin labeling and single molecule optical microscopy. Biochim Biophys Acta 1610: 231–243. PubMed Google Scholar A Janus molecule (or Janus-faced molecule) is a molecule which can represent both beneficial and toxic effects. Examples are nitrous oxide [1] and cholesterol.
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Authors; Approaches by pulse EPR spin labeling and single molecule optical microscopy. Biochim Diphenyl Diselenide a Janus-Faced Molecule. J. Br az.
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1 Although selenium has important physiological roles in mammalian Hydrogen sulfide (H₂S) is a Janus-faced molecule. On one hand, several toxic functions have been attributed to H₂S and exposure to high levels of this gas is extremely hazardous to health. On the other hand, H₂S delivery based clinical therapies are being developed to combat inflammation, visceral p … A rare disk-like single-molecule magnet (SMM) exclusively bridged by end-on azides with a spin ground state of S = 14 was prepared by the reaction of a divalent FeII precursor with Me3SiN3 under basic conditions. AC magnetic susceptibility studies revealed unusual, “Janus”-faced SMM behavior for the dried a Diphenyl Diselenide a Janus-Faced Molecule. J. Br az.
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2021-4-1 · Pages in category "Molecules" The following 20 pages are in this category, out of 20 total. This list may not reflect recent changes (). It was believed that the Janus-faced molecule serves as an antioxidant or a prooxidant depending on its local concentrations. At lower concentrations, H 2 S exerts beneficial effects like protective effects in the cardiovascular system as we mentioned before, while at higher concentrations, H 2 S exhibits a variety of deleterious/cytotoxic The group has created double-faced gamma PNAs called Janus gamma PNAs.